With its doughnut-shaped laser, MINFLUX can track kinesin even when it’s running at 550 nanometres per second. MINFLUX builds on the success of stimulated emission depletion microscopy, a Nobel-prizewinning method that bypasses the diffraction limit of light microscopy. Observing kinesin in its natural cellular habitat is tricky because it walks so fast. ![]() Kinesin, which looks like a twisted stalk wearing oversized shoes, is one of those molecular motors that drive crucial processes, including cell division, signalling and transport. ![]() Reference: BMC Medicine paper Features & opinion A microscope for walking proteinsĪ super-resolution microscope called MINFLUX can track moving motor proteins even amid the bustle of living cells. “The current system is not sustainable,” says study co-author Tibor Varga. Suggested remedies include universal journal guidelines, free-format submissions or a ‘golden middle’ solution that allows researchers to submit manuscripts that abide by minimal structural requirements, such as total word count. If current journal practices don’t change, the authors estimate that reformatting could cost about $2.5 billion between 20. An analysis shows that, in 2021, the global price tag on all of that busywork was US$230 million - just for biomedical journals. Scientists are spending millions of dollars’ worth of time reformatting rejected papers for submission to alternative journals. Reference: Science paper Millions wasted on reformatting papers Scientists urge caution for people looking to boost their own health - it’s too soon to say whether the findings translate to humans. Similar effects on the hallmarks of ageing were seen in Caenorhabditis elegans worms and middle-aged rhesus monkeys ( Macaca mulatta). ![]() They also seemed healthier, with improvements in muscle endurance and strength. When researchers gave taurine supplements to mice, their lifespans increased by around 10% compared with a control group. Reference: Science paper Taurine supplement boosts animal lifespanįeeding large amounts of taurine - a common ingredient in energy drinks - to mice, worms and monkeys helps them to live longer, healthier lives. In cities, the effect was reversed: animals roamed less widely, maybe because they were less often frightened by cars. (Christopher Furlong/Getty Images) Animals hit the road during lockdownsĬOVID-19 lockdowns offered a natural experiment to find out why animals usually tend to avoid roads - is it because of the vehicles, or the infrastructure? Tracking data from 43 mammal species around the world showed that most animals explored more of the landscape when vehicle movement was limited. Wild mountain goats roamed the streets of Llandudno, Wales, in 2020. Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here.
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